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The findings suggest that tissue macrophages may not represent a significant contributor to the long-term reservoir of replication-competent HIV in people on ART. Several possible caveats to the study are also noted, such as the relatively small number of participants and the possibility that inflammatory liver disease which had prompted the need for transplantation in most cases influenced that makeup biggest white and black assess the liver macrophage population, i.
Despite these limitations, the study adds novel evidence to the debate regarding the role of macrophages in HIV persistence. This article was originally published by TAG on Sept.
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